Otay Mesa Holidays

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Our guide on where to stay in Otay Mesa

Find the best Otay Mesa areas and neighborhoods for the activities you enjoy most. Learn more about Otay Mesa
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Downtown San Diego

2 out of top 10 points of interest in this area
4.5/5(100 area reviews)

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Port of San Diego and San Diego Civic Theatre are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Find hotels in Downtown San Diego

Our pick of the best Otay Mesa Hotel Deals

The Dana on Mission Bay
The Dana on Mission Bay
3.5 out of 5
1710 W Mission Bay Dr, San Diego, CA
Fully refundableReserve now, pay when you stay
The price is AU$268 per night from 30 Jan to 31 Jan
AU$268
includes taxes & fees
30 Jan - 31 Jan
8.6/10 Excellent! (3,082 reviews)
"nice hotel quiet grounds"

Reviewed on 26 Jan. 2025

The Dana on Mission Bay
Best Western Seven Seas
Best Western Seven Seas
3 out of 5
411 Hotel Circle South, San Diego, CA
Fully refundableReserve now, pay when you stay
The price is AU$168 per night from 30 Jan to 31 Jan
AU$168
includes taxes & fees
30 Jan - 31 Jan
7.6/10 Good! (2,589 reviews)
"Friendly staff. Clean property. Quiet community."

Reviewed on 27 Jan. 2025

Best Western Seven Seas
Hyatt Regency Mission Bay Spa and Marina
Hyatt Regency Mission Bay Spa and Marina
4 out of 5
1441 Quivira Rd, San Diego, CA
Fully refundableReserve now, pay when you stay
The price is AU$374 per night from 13 Feb to 14 Feb
AU$374
includes taxes & fees
13 Feb - 14 Feb
8.4/10 Very Good! (1,471 reviews)
"Beautiful property, location, and views. I attended a conference at the resort, and the facilities and staff were very good. Finding dinner was a problem for me. The "Market" and the small restaurant near my room both closed at 5pm, before I got out of the conference. The only food option at the ..."

Reviewed on 26 Jan. 2025

Hyatt Regency Mission Bay Spa and Marina
See all 4,545 properties in Otay Mesa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays

All Inclusive Holidays

All Inclusive Holidays
Cheap Holidays

Cheap Holidays

Cheap Holidays
beach holidays

Beach Holidays

Beach Holidays

Frequently asked questions

How much does an Otay Mesa holiday package cost?
Starting from as low as , a holiday package is your ticket to cheaper travel. Create your own Otay Mesa escape by choosing from our wide range of hotels, airfares and rental cars.
How do I get a cheap travel package to Otay Mesa?
Our Otay Mesa holiday packages mean plenty of savings for the savvy wanderer. For the best deal, simply bundle your hotel, flights and extras (such as activities) into a neat and tidy package. But impressive bargains are only the start of your next amazing adventure. When you book with Expedia, you’ll have more than 550 air carriers and 1 000 000 hotel options all over the world to pick from. No matter your budget or style, there’s a package that’s perfect for you.
Where should I stay in Otay Mesa?
A getaway to Otay Mesa wouldn’t be complete without paying a visit to North Island Credit Union Amphitheatre, Aquatica and White Water Canyon. Spend your evenings close to these tourist attractions and make sightseeing simple.
What are the top hotels in Otay Mesa?
Book a stay at Holiday Inn Express Hotel & Suites San Diego Otay Mesa, an IHG Hotel. It’s one of this neighbourhood’s most sought-after hotels. Another reputable option in Otay Mesa is Quality Suites San Diego Otay Mesa.
How far in advance should I book my Otay Mesa holiday?
Your best bet is to book early. Air carriers typically release flights around a year prior to departure, and this is an ideal opportunity to score some rock-bottom prices. Boss just told you to take your holiday time next month? That’s alright! Expedia are never short on fantastic deals to send you on the getaway of your dreams, at a price you can afford.
What does an Expedia Otay Mesa travel package include?
It comes down to what you want. If you’re travelling alone, you might decide to bundle flights and hotels. Bringing the entire family to Otay Mesa? A travel package that includes rental cars, flights and hotels might be a better fit. Expedia gives you the flexibility and freedom to tailor-make your travel package.
What should I know before booking an Otay Mesa travel package?
When you book your flights, hotels and car rentals together, you’ll land terrific discounts. Whether you’re organising an island getaway in a villa or prefer to stay in a cosy apartment in the city, Expedia can help make it happen.
Can I choose my airline with an Otay Mesa Expedia holiday package?
You can, and with over 550 airlines to select from worldwide, you have loads of choice. Look through the available options and find out which airline best suits your needs and budget.
If I'm not able to travel, can I cancel my Otay Mesa holiday package?
Don’t worry if you’re rethinking your Otay Mesa holiday package — it’s possible to change or amend your booking. And if you’ve booked it within 24 hours, you may be able to do it for free. However, bookings made more than 24 hours ago may incur fees from your hotel, airline or car rental company. We get that life can sometimes throw a spanner in the works, so make your way to our Customer Service Portal if that happens. When you’re ready to make changes, we’re ready to help.

Discover the most popular places to visit in Otay Mesa

San Diego Zoo which includes a pond, zoo animals and landscape views

San Diego Zoo

4.5/5(26 reviews)

One of the largest zoos in America housing around 4000 creatures, San Diego Zoo offers an enchanting and educational experience for visitors of all ages.

San Diego Zoo
San Diego Convention Center

San Diego Convention Center

4.5/5(13 reviews)

During your trip, find out what's happening in San Diego Convention Center, a top convention centre in San Diego. Experience the area's acclaimed art galleries and fascinating museums.

San Diego Convention Center
Mission Beach

Mission Beach

4/5(30 reviews)

A seaside village and a popular spot for holiday-makers for over a century, which today still retains its antique charm.

Mission Beach

Activities

Crossing Borders: Tijuana Day Trip from San Diego

Crossing Borders: Tijuana Day Trip from San Diego

AU$150
per adult
100% of travellers recommend
Crossing Borders: Tijuana Day Trip from San Diego
San Diego USS Midway with Waterfront Walking Tour

San Diego USS Midway with Waterfront Walking Tour

AU$63
per adult
San Diego USS Midway with Waterfront Walking Tour
Kayak on the San Diego Bay

Kayak on the San Diego Bay

AU$32
per adult
Kayak on the San Diego Bay
See all activities in San Diego
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.